All posts by Nutricia Metabolics

What is GMP?

You’ve likely seen ‘GMP’ on a Phenyketonuria (PKU) or Tyrosinemia formula label or heard about it through your dietitian. But what exactly is it and why is it getting so popular?GMP can be used as a protein source for PKU and Tyrosinemia formulas. GMP, short for glycomacropeptide, is a peptide – a type of short protein. Peptides typically consist of shorter chains of amino acids, whereas true proteins are larger and more complex structures.

GMP is a byproduct of the cheesemaking process. Cheese is made from milk and contains intact protein. Milk consists of two types of proteins: casein and whey. During the cheese making process, the whey is separated from the casein; the casein part is what is used for cheese, the whey part is used for other purposes. GMP is found in the whey portion and must be filtered out to be used as an ingredient in formulas.

Contrary to other proteins, pure GMP does not contain phenylalanine (PHE), tyrosine (TYR) and a couple of other amino acids. That’s why it is a suitable protein source for PKU and Tyrosinemia formulas. However, through the process of isolating GMP from the whey part of the milk, some very small amounts of PHE and TYR cannot be filtered from the actual GMP and are part of the GMP ingredient used in PKU and Tyrosinemia formulas.

GMP by itself lacks certain amino acids that are important for growth and development. These amino acids must be added to the formulas so that PKU and TYR formulas are appropriate for individuals with PKU or Tyrosinemia. That’s why you see GMP and free amino acids listed as ingredients on your PKU and Tyrosinemia formula label.

You may have noticed slight variations in the PHE content when comparing GMP formulas (for example, between 10‐18 mg PHE per 10 g protein equivalent). Healthcare professionals have told us, that the differences are so small that they are clinically not relevant, and studies support this. This means that if a GMP‐based product is appropriate for someone with PKU or Tyrosinemia, the slight differences in PHE content are not important.

GMP is still a growing concept, but several studies support that GMP‐based products are safe and appropriate for most individuals with PKU or Tyrosinemia. GMP‐based products have a milder taste, and that milder taste is often preferred over amino acid‐based products. Finding a formula you or your child like is very important as that can certainly help with diet adherence. In addition, a small number of studies also report that patients feel fuller when consuming a GMP‐based formula.

A small number of clinical studies are also looking into other benefits of GMP‐based products in metabolics. However, the results of these studies are inconclusive. More research is needed to provide definite answers.

For some people with PKU or Tyrosinemia, the amount of PHE in GMP‐based formulas may be too high. Rest assured that formulas that are based 100% on amino acids (with no GMP) provide you or your child with all the nutrients needed for proper growth and development, including important vitamins and minerals for bone health. But of course, your dietitian can advise you on which formula is best for you or your child.

Want to find a GMP‐based formula? You’ve come to the right place!

Check out the variety of GMP‐based formulas that Nutricia has to offer: click on a product above  and read our blog on GMP‐based products from Nutricia.  READ NOW

Always talk to your dietitian before making any diet changes – and contact us if you have any questions about metabolic formulas. Visit www.MedicalFood.com for more information.

Written by: Ulrike Reichert, MS

Director Medical Affairs Keto/Metabolics Nutricia North America

 

 

PhenylAde GMP READY, PhenylAde GMP Drink Mix, and PhenylAde GMP Mix-In are medical foods for the dietary managment of proven Phenylketonuria (PKU) and must be used under medical supervision.  TYR Lophlex LQ is a medical food for the dietary management of proven Tyrosinemia  and must be used under medical supervision. 

 

Nutricia offers variety and choice in GMP‐based products:

At Nutricia, we are dedicated to providing more choices to more people. We have recently added new GMP‐based products to our portfolio. To read more about what GMP is, click HERE.

For those of you who want an overview of what is available in GMP‐based products from Nutricia, we made this quick reference guide. Get inspired to find your favorite one!

GMP‐based products for Phenylketonuria

(click the product box to learn more)

GMP‐based products for Tyrosinemia

Get READY for a Difference You Can Taste! No Mixing! GMP‐based powder to create the “Ultimate PKU Protein Shake” Virtually tasteless and odorless to mix in beverages or semi‐solid food Mild taste to mix in beverages or semi‐solid food

 

Always talk to your dietitian before making any diet changes – and contact us if you have any questions about metabolic formulas. Visit MedicalFood.com for more information.

Your Nutricia Metabolics Team

 

 

 

 

 

PhenylAde GMP READY, PhenylAde GMP Drink Mix, and PhenylAde GMP Mix-In are medical foods for the dietary managment of proven Phenylketonuria (PKU) and must be used under medical supervision.  TYR Lophlex LQ is a medical food for the dietary management of proven Tyrosinemia  and must be used under medical supervision. 

 

Are you READY?

Are you READY?

New at Nutricia is PhenylAde® GMP READY, a ready‐to‐ drink PKU formula, providing 10 g protein equivalent and 110 kcal in one drink box (8.5 fl oz). It is also the only GMP‐ based formula with both DHA and EPA, two important omega‐3 fatty acids missing in the PKU diet.

PhenylAde GMP READY:

  • Offers an enjoyable, neutral flavor with a smooth texture for easy drinking

  • Contains GMP, which is made from an intact protein source and is naturally low in phenylalanine.   Click HERE to learn more about GMP.

  • Provides an excellent source of both calcium and vitamin D, two nutrients that help build and maintain strong bones and teeth

A ready‐to‐drink formula can make your life so much easier: from grabbing it in the morning for your breakfast drink to throwing it in the lunch bag for school or work or when you travel. We all have busy lives, and PhenylAde GMP READY is here to provide great nutrition in a convenient drink box.

Take the taste challenge as some of your fellow PKUers have done and let us know your thoughts!

GET READY TODAY!

Always talk to your dietitian before making any diet changes – and contact us if you have any questions about metabolic formulas. Visit MedicalFood.com for more information.

Your Nutricia Metabolics Team

 

 

 

PhenylAde GMP READY is a medical food for the dietary management of proven Phenylketonuria (PKU) and must be used under medical supervision.

Loprofin Pasta and the delicious taste of Italy

Ever wonder where Loprofin Pasta is made?

Meet Lorenzo Mennucci. The Mennucci family began making Loprofin Pasta almost 50 years ago in Tuscany. It is now in its fifth generation and is managed by Lorenzo Mennucci. In 1877, Giuseppe Mennucci started making pasta in a small grocery store in the countryside of Tuscany. At that time, the process of making and drying the pasta was carried out in the courtyard under the sun. This all nearly ended during the Second World War, when the company was bombed and partially destroyed. After the bombing, the Mennucci family was quick to rebuild the factory. During the rebuilding process, all pasta machines that were not destroyed were moved into local homes near Tuscany to maintain the production of pasta.

The Mennucci family are very passionate about using the highest quality of ingredients which are mainly sourced from Italy. There are only four ingredients in low protein pasta which are mainly starches; corn, potato, rice and coloring (annatto). Lorenzo believes that when there are so few ingredients in a product it is important that you use the highest quality of ingredients.

The main difference in the production of low protein pasta and ordinary pasta is that gluten is the protein that binds the dough in ordinary pasta. For low protein pasta, steam is used instead to bind the starches together to make a dough. Low Protein Pasta is made using spring water that comes from the Tuscan mountains.

See for yourself where our Loprofin Pastas are made in this video  of the Mennucci family!

View recipes made with Loprofin Low Protein Pasta at MedicalFood.com/Recipes 

New GMP-based option for Tyrosinemia!

TYR Lophlex GMP Mix-In is an unflavored product low in phenylalanine and tyrosine with glycomacropeptide (GMP). It is indicated for the dietary management of proven Tyrosinemia in individuals over 1 year of age.

TYR Lophlex® GMP Mix-In is your protein on-the-go:

  • Mixes easily with flavored drinks and blends easily into foods to add variety

  • Low calorie option with only 40 calories per 10 g sachet

  • Less than 0.5 g of sugar per pouch

  • Tastes great with no artificial flavors or colors

  • An easy way to add glycomacropeptide (GMP), made from a whole protein source, to your TYR diet

What is GMP?

Glycomacropeptide, or GMP for short, is derived from a whole protein source. It is naturally low in phenylalanine and tyrosine, and with the addition of certain amino acids, it makes a suitable source of protein for those with Tyrosinemia. Your dietitian will help determine how much to take.

What makes TYR Lophlex GMP Mix-In special?

TYR Lophlex GMP Mix-In tastes great and gives you the flexibility to boost your protein!

  • You can easily mix into foods, drinks or your current TYR formula

  • Each 10 g sachet is only 40 calories

Talk to your dietitian today and request a sample.

TYR Lophlex® GMP Mix-In is a medical food for the dietary management of proven Tyrosinemia and must be used under medical supervision.

©2019 Nutricia North America.

Happy New Year!

Happy New Year!

The start of a new year is a great time to re-commit to better diet management.

Improving your metabolic diet is different for everyone. It can range from calling your clinic for the first time in years to making simple improvements such as:

 

  • Eating more fresh fruits and vegetables

  • Drinking the full amount of formula

  • Finding a formula you enjoy drinking

  • Sending in blood spots more frequently

  • Trying new low protein recipes

Nutricia is proud to offer support services to help you achieve some of your dietary goals.

 Our Nutricia Connect™ program is here to provide support at various stages of life’s journey.  We offer an array of low protein recipes, educational tips and resources and a team of professionals who can assist you or your loved one to get back on-diet.

Additionally, Nutricia’s team of formula coverage specialists can review your insurance and answer any questions you may have about formula coverage.

Connect with them today by emailing Coverage@Nutricia.com or by calling 1-800-605-0410.

Improve Your Metabolic Diet Today


About Us:

Nutricia Metabolics provides a variety of formula options for inborn errors of metabolism, including Phenylketonuria (PKU), Maple Syrup Urine Disease (MSUD), Tyrosinemia (TYR), Homocystinuria (HCU), Urea Cycle Disorders (UCD), Glutaric Aciduria Type-1 (GA-1), Isovaleric Acidemia (IVA), Propionic Acidemia (PA), Methylmalonic Acidemia (MMA) and Fatty Acid Oxidation Disorders (FAODs). Learn more at www.MedicalFood.com

 

 

NOTE: All Nutricia Metabolics products are medical foods and must be used under medical supervision. Always consult your metabolic healthcare professional prior to making any changes in your metabolic diet plan.

Loprofin Baking Mix – A versatile low protein baking mix

Loprofin Mix is an all‐purpose, low protein baking mix, great for cooking and home‐made pastries. A packet of yeast is provided in each box, making baking easy, especially bread. Nutricia also offers Loprofin Chocolate Cake Mix, great for any chocolate cake or muffin recipe. Tasty recipes, such as breads, naan, cupcakes, gingerbread and many more can be found here!

Loprofin Mix is a great substitute for Wel‐Plan Baking Mix, which is unfortunately no longer available. Several low protein expert chefs shared that they substitute Wel‐Plan Baking Mix with Loprofin Mix at a 1:1 ratio. For example, if a recipe asks for one cup of Wel‐Plan, you would use one cup of Loprofin Mix. We have also test‐baked a few low protein bread recipes from “Apples to Zucchini”, a cookbook by Virginia Schuett and Dorothy Corry, and confirmed that Wel‐Plan can be substituted at a 1:1 ratio with Loprofin Mix for many bread recipes. Check out these recipes with Loprofin Mix that work for making bread – with or without a bread machine!

Many of you relied on Maddy’s Homestyle baking mixes as convenient, quick mixes. We developed recipes where you can use the Loprofin Mix to make the same baked goods. New Loprofin recipes such as,  sugar cookies, banana bread and blueberry muffin, to list just a few can be found here.

Look out for our future blogs on holiday cooking and baking, as well as making the low protein kitchen convenient, quick and tasty!

Happy Baking!

Tips for a Low Pro Friendly Thanksgiving

fb-thanksgiving

The holidays can be an exciting time of year. However, they can be a bit challenging for someone on a restricted diet as most festivities center around food. This blog focuses on tips for managing a restricted diet during the holiday season.

The most important thing to do is plan ahead.  The more you know in advance, the better you can plan.

Here are some questions to ask yourself:

  • Where will I be spending the holidays and how long will the trip be?

  • Do I have enough formula so I do not run out while away over the weekend?

  • Am I dining at home or at someone else’s home?

  • Will I be preparing the food or will someone else?

Once you know more about what your day/weekend will consist of, you can make a plan.

One key thing is to plan the menu in advance.  If you are not dining at home, but at a friend’s or relative’s home, it will be important to ask what is being served, then…

  • Ask if you can bring a side dish (one that is suitable for you, but enough for everyone to share).

  • Let them know about your dietary needs so they can omit or serve items on the side that are not low protein friendly, like cheese or bread crumbs.

  • See if you can access the kitchen to re-heat or make additional low-protein items for the holiday meal.

Get Creative!

Many traditional holiday favorites can be modified to reduce the protein while still keeping the taste and texture you and others love.

Here is a simple recipe for a popular dish with small changes to lower the protein content – this dish is sure to become a family staple at your holiday meal:

 

Reduced Protein Mashed Potatoes

2 cups (248 g), Cauliflower, florets
2 cups (312 g), White potato, peeled and cut into pieces
1 cup (156 g), Parsnips, peeled and cut into pieces
¼ cup (56 g), Non-dairy creamer, liquid
2 tablespoons (28 g), Margarine, dairy-free
To taste (2-3 g), Salt and pepper

Directions

  1. Boil potato and parsnip in a large pot until they begin to soften.
  2. Add cauliflower and continue to cook until soft and tender.
  3. Drain water.
  4. Place all ingredients in a food processor and blend until smooth.
  5. Salt and pepper to taste.

Makes 7 servings

Per Recipe:

700 calories

13.8 g protein

709 mg leucine

499 mg phenylalanine

337 mg tyrosine

 

Per Serving:

100 Calories

2 g protein

101 mg leucine

71 mg phenylalanine

48 mg tyrosine

End your holiday meal on a sweet note with this low protein dessert.  This is a dish everyone at your holiday gathering is sure to enjoy!

 

Easy Pumpkin Pudding (recipe developed by Sarah Marshall)

 

1 fluid ounces            Water

7 fluid ounces             Coconut Milk (full fat, canned coconut milk required to get pudding-like consistency)

6  each                        Whole pistachios (for flavor – to be strained out later)

½ tablespoon             Brown sugar

¼ teaspoon                Pumpkin pie spice (or blend cinnamon, ginger and nutmeg)

½ teaspoon                Vanilla flavoring

½ cup                          Loprofin Rice

 

 

Directions

  1. In a small saucepan, add 1 oz water & 7 oz coconut milk and 6 pistachios.
  2. Bring to a boil. Immediately when it begins boiling, add brown sugar, vanilla and pumpkin pie spice and stir.
  3. Add Loprofin Rice. Stir. Cover and lower heat to simmer covered for 10 minutes.
  4. Once rice is cooked remove pistachio pieces.
  5. Serve warm or cold.

 

Makes 2 servings

 

Per Recipe

534 calories

4.1 g protein

306 mg leucine

207 mg phenylalanine

124 mg tyrosine

 

Per Serving

267 calories

2 g protein

153 mg leucine

104 mg phenylalanine

62 mg tyrosine

And most of all…

Holidays do not have to be all about food.  Make your holidays memorable with family traditions, such as a family football game or a checkers tournament.

Happy Thanksgiving from

Nutricia_Metabolics_Logo 2

Help Support PKU Awareness with a #Toast2PKU

Raise your glass and be counted!

In support of PKU Awareness Day on December 3, 2018, Nutricia is challenging you to POST YOUR TOAST!

For each tagged post on Facebook or Instagram with #Toast2PKU, Nutricia will donate $5 to the National PKU Alliance to help support their mission to improve the lives of families and individuals associated with PKU through research, support, education and advocacy, while ultimately seeking a cure.*

So don’t delay, post and tag your  toast today!



You can also show your support with a direct donation to the NPKUA


Note: Facebook and Instagram are in no way affiliated with Nutricia and have not endorsed this contest or Nutricia products. Only tagged posts made between November 15, 2018 and December 3, 2018 11:59pm  will be counted toward the donation to the National PKU Alliance.

*Nutricia will cap the donation to a maximum of 600 posts during this time period or up to $3000.

 

 

Tips for a Low Protein Friendly Halloween

Trick or Treat?

For children with an inborn error of  metabolism, Halloween celebrations can be tough since protein-containing candy and snacks tend to be the classic party staples. Additionally, these celebrations can be scary on parents as they want their children to fully enjoy in the festivities while maintaining their dietary restrictions.

Here are a few tips, resources, and recipes to help make Halloween fun while staying on a diet low in intact protein:

First:

  • Speak with teachers or other parents about what your child can and cannot have at Halloween parties or school

  • Also talk with your child about the importance of staying on diet and remind them to check with you to determine if a particular food or candy is

Now to the Fun Stuff:

  • Get creative with Halloween Have non-food treats to hand out at home or at school. Think dollar store toys, stickers, party favors, and coloring books.

  • Plan an alternative activity to trick-or-treating, such as Halloween slumber party, game night, craft party, or a scavenger

  • Supply low-protein treats for your child’s Halloween parties and festivities so he/she has something to enjoy and doesn’t feel left out – View Halloween Cupcake Recipe

  • Consider having a “swap-party” where your child can swap candies he/she cannot have for “allowed” This way everyone gets what they want!

  • Make your child’s metabolic formula festive! Serve it in a Halloween- themed cup, use fun straws, or add some orange food

Post Your Formula ‘Dressed-Up’ for Halloween and TAG Nutricia! 

#NutriciaMetabolicNutrition      

Halloween Low Protein Cupcakes

jack-o-lantern-228

Surprise a special someone or treat yourself to a Halloween cupcake. These cupcakes are made with Loprofin Baking Mix. They are easy to make and great for at home, work or parties.

 

Makes 10 cupcakes

 

Ingredients

  • 88 g (3/4 cup ) Loprofin Baking Mix
  • 1/4 cup white sugar
  • 1 teaspoon egg replacer
  • 1 teaspoon baking powder
  • 5 ounces of water
  • 1/4 cup margarine
  • 1/2 teaspoon vanilla extract
  • 4 drops orange food coloring
  • 1/2 cup white frosting
  • 20 candy corns

 

Method:

 

  1. Preheat oven to 350°F (180°C)
  2. Cream together margarine and sugar until light and fluffy
  3. Add Loprofin Baking Mix, egg replacer, and baking powder into the creamed mixture and mix well
  4. Add water, vanilla extract and orange food coloring gradually, mix until smooth
  5. Spoon batter into paper cups filling each cup about 2/3 full and bake for approximately 10-15 minutes
  6. Let cool on a baking rack
  7. Decorate with frosting and candy corn
Nutritional Information Per Cupcake
Calories 155
Protein 0.1 g
Phenylalanine 4 mg
Leucine 7 mg

 

Note:  Any additional frosting or decorations may add additional protein, phenylalanine, leucine or calories, be sure to read labels and account for any topping or decorations.

All Nutricia products shown are for the dietary management  of inborn errors of metabolism and must be used under  medical supervision. Please consult your metabolic healthcare professionals prior to making any changes to your diet.